Associate Professor
School of Arts & Sciences
cbieszczad@colby-sawyer.edu
603.526.3061
Joined the faculty in 2008. Received Ph.D. in Pharmacology and Toxicology from Dartmouth Medical School in 1999. Areas of expertise include pharmacology, toxicology, microbiology, cancer biology and anatomy & physiology.
De Biasio, A., Vrana, J.A., Zhou, P., Qian, L., Bieszczad, C.K., Braley, K.E., Domina, A.M., Weintraub, S.J., Neveu, J.M., Lane, W.S., Craig, R.W. N-Terminal Truncation of Antiapoptotic MCL1, But Not G2/M-Induced Phosphorylation, Is Associated With Stabilization and Abundant Expression in Tumor Cells, J. Biol. Chem. 282(33): 23919-36, 2007.
Vrana, J.A., Bieszczad, C.K., Cleaveland, E.S., Ma Y., Park, J.P., Mohandas, T.K., Craig, R.W. An MCL1-Overexpressing Burkitt Lymphoma Subline Exhibits Enhanced Survival on Exposure to Serum Deprivation, Topoisomerase Inhibitors, or Staurosporine But Remains Sensitive to 1-beta-D-arabinofuranosylcytosine, Cancer Research. Feb 1;62(3):892-900, 2002.
Townsend, K.J., Zhou, P, Bieszczad, C.K., Lowrey, C. and Craig, R.W. Regulation of MCL1 by Serum Response Factor / Elk-1-Mediated Mechanism Links Expression of a Viability-promoting Member of the BCL2 Family to Proliferation/Differentiation, J. Biol. Chem., 274(3):1801-13, 1999.
Zhou, P., Qian, L., Bieszczad, C.K., Noll, W.W., Noelle, R., Binder, M., Levy, N.B. and Craig, R.W. Mcl-1 in Transgenic Mice Promotes Survival in a Spectrum of Hematopoietic Cell Types, Allowing for Immortalization in the Myeloid Lineage, Blood, 92(9):3226-39, 1998.
Zhan, Q., Bieszczad, C.K., Bae, I., Fornace, A. Jr. and Craig, R.W. Induction of Bcl-2 Family Member Mcl-1 as an Early Response to DNA Damage, Oncogene 14(9), 1031-1039, 1997.