Chery A. Whipple

Assistant Professor
School of Arts & Sciences
chery.whipple@colby-sawyer.edu
603.526.3679

Joined the faculty in 2017. Professor Whipple has a B.S. in Biology from Lake Erie College as well as a M.S. in Education and a Ph.D. in Genetics from the University of New Hampshire. Following her graduate work, Professor Whipple spent 12 years researching pancreatic and skin cancer at Dartmouth’s Norris Cotton Cancer Center before joining CSC. She is excited to share her extensive research experience with her students at Colby-Sawyer. Professor Whipple teaches courses in biology, microbiology, genetics, anatomy and physiology and laboratory techniques. She has recently developed two new integrative study courses; the first is a field course on tropical communities (in Belize) and the second is a cancer epidemiology course.

Professor Whipple is particularly interested in guiding undergraduate research projects and is an instructor in the NH-INBRE supported summer research course. Professor Whipple continues to study cancer cell lines at Colby-Sawyer focusing on the interaction between the cancer cells of a tumor and the normal cells that surround the tumor and how we might be able to hinder aberrant communication between them. Another area of interest, which several new students are investigating alongside Professor Whipple, is impact of emerging groundwater contaminants on indicator species (such as the non-parasitic worm, and model organism, C. elegans). read more…

Areas of Expertise & Research Interests

  • Anatomy & Physiology
  • Biology
  • Environment
  • Environmental pollutants
  • Epigenetics
  • Ethics
  • Genetics
  • Molecular biology
  • Nursing
  • Tumor microenvironment

Publications

  • Pandey, A., Peri, S., Thacker, C., Whipple, C., Collins, J.J., and Mann, M. (2003). Computational and experimental analysis reveals a novel SRC family kinase in the C. elegans Genome. Bioinformatics 19(2), p169-172.
  • Aikawa, T., Whipple, C., Lopez, M., Gunn, J., Young, A., Lander, A., and Korc, M. (2008). Glypican-1 Modulates the Angiogenic and Metastatic Potential of Cancer Cells. JCI. 118 (1). p89-99.
  • Whipple, C. and Korc, M. (2008). Targeting Angiogenesis in Pancreatic Cancer: Rationale and Pitfalls. Langenbecks Arch Surgery. 393 (6). p901-10.
  • Whipple, C., Lander, A., and Korc, M. (2008). Discovery of a novel molecule that regulates tumor growth and metastasis. The Scientific World Journal. (8). p1250-3.
  • Whipple, C. and Korc, M. (2011). Angiogenesis signaling pathways as targets in cancer therapy. Intercellular Signaling in Development and Disease. 1st Edition. Academic Press, Waltham, MA. p401-411. Reprinted from Handbook of Cell Signaling, 2nd Edition. (2009).
  • Whipple, C. and Korc, M. (2012). A KrasG12D-Driven Genetic Mouse Model of Pancreatic Cancer Requires Glypican-1 for Efficient Proliferation and Angiogenesis. Oncogene. 31 (20): 2535-44.1
  • Whipple, C. and Brinckerhoff, C. BRAFV600E melanoma cells secrete factors that activate stromal fibroblasts and enhance tumorigenicity. Submitted to the Journal of Investigative Dermatology, April 2014.
  • Thomas AA, Fisher JL, Rahme GJ, Hampton TH, Baron U, Olek S, Schwachula T, Rhodes CH, Gui J, Tafe LJ, Tsongalis GJ, Lefferts JA, Wishart H, Kleen J, Miller M, Whipple C., de Abreu FB, Ernstoff MS, Fadul CE. Neuro Oncol. (2015). Regulatory T cells are not a strong predictor of survival for patients with glioblastoma. Jun; 17(6). p801-9.
  • Whipple, C. (2015). Tumor talk: understanding the conversation between the tumor and its microenvironment. Cancer Cell and Microenvironment. 2: e773. doi: 10.14800/ccm.773
  • Whipple, C., Boni, A., Fisher, J., Hampton, T., Yan, S., Tafe, L., Tsongalis, G., Fadul, C. and Ernstoff, M. (2016). MAPK Pathway has a critical role in regulating immunological properties of BRAF mutant cutaneous melanoma cells. Melanoma Research. 26 (3). p223-35.

Presentations & Poster Presentations

  • Whipple, C. (2008). Environmental carcinogens and the importance of the sugar molecule, Glypican-1, in the development of pancreatic cancer. Kean University. Union, NJ.
  • Whipple, C. and Korc, M. (2011). GPC-1 promotes tumor growth and angiogenesis in a KrasG12D-driven mouse model of pancreatic cancer. American Association for Cancer Research, 102nd Annual Meeting Orlando, FL.
  • Whipple, C. and Korc, M. (2011). Glypican-1 enhances tumor growth and angiogenesis in a KrasG12D-driven mouse model of pancreatic cancer. Norris Cotton Cancer Center Grand Rounds, Lebanon, NH.
  • Whipple, C (2018). Tumor Talk: understanding the conversation between the tumor and its microenvironment. Franklin Pierce University. Rindge, NH.
  • Whipple, C. Characterization and evolutionary relationships of src-1 and src-2 in Caenorhabditis elegans. East Coast Worm meeting. UNH. June 15, 2002.
  • Whipple, C. Function and Expression of src-1 and src-2 in C. elegans. International C. elegans Conference. UCLA. June 24-29, 2005.
  • Zagorchev L, Moodie K, Shworak N, Whipple C., Korc M, Mulligan-Kehoe MJ. The Anti-angiogenic Activity of rPAI-123 Inhibits Pancreatic Ductal Adenocarcinoma Tumor Growth. Gordon Research Conference, Angiogenesis and Microcirculation, Newport, RI, August, 2007.
  • Whipple, C., Aikawa, T., Lopez, M., Gunn, J., Lander, A., and Korc, M. (2008). Glypican-1 is crucial for the angiogenic and metastatic potential of pancreatic cancer cells. AACR Annual Meeting. San Diego, CA.
  • Anna Testorf and Whipple, C. (2018). Toxicity of aspartame studied in C. elegans. American Association for the Advancement of Science (AAAS) Annual meeting, Austin, Texas.
  • Mikey Rieger and Whipple, C. (2018). A study of NaNO2 effects on Caenorhabditis elegans. AAAS Annual meeting, Austin, Texas.
  • Emma Tysinger and Whipple, C. (2018). The effect of temperature on development and survival behaviors over multiple generations of Caenorhabditis elegans. AAAS Annual meeting, Austin, Texas.
  • Miriam Viazmenski and Whipple, C. (2018). Examining the individual and combined effects of Round-Up’s disclosed ingredients on the activity levels of C. elegans. AAAS Annual meeting, Austin, Texas.
  • Fiona Gail and Whipple, C. (2018). Effects of microbiome diversity on C. elegans strains with HIF mutations. AAAS Annual meeting, Austin, Texas.
  • Katherine Axelrod and Whipple, C. (2018). Optimization of RNA extraction and cDNA synthesis in C.elegans.
  • Whipple, C. (2019). The emergent contaminant, PFOA, and its impact on the nematode Caenorhabditis elegans’ viability and growth. NH-INBRE Annual meeting, Bretton Woods, NH.
  • Poster presentations: Seebeck, M., Mayberry, A., Jukosky, J., and Whipple, C. (2019). Observing the exposure of Perfluoroalkyl Substances (PFAS) in Caenorhabditis elegans lethality, fecundity and motility. NH-INBRE Annual meeting, Bretton Woods, NH.
  • Stephens, C., Kelly, M., Bishop, M., Whipple, C., and Jukosky, J. (2019). The effect of low level imidacloprid exposure on motor activity in bumblebees. NH-INBRE Annual meeting, Bretton Woods, NH.
  • Kelly, M. Stephens, C., Bishop, M., Whipple, C., and Jukosky, J. (2019). Screening bumblebees for fungal pathogens and pesticide residues. NH-INBRE Annual meeting, Bretton Woods, NH.
  • Belizaire, M., Padilla, R., Shapkota S., Jukosky J., Whipple, C. (2019). The effect of the anti-diabetic drug metformin on melanoma cell viability and motility. NH-INBRE Annual meeting, Bretton Woods, NH.

Affiliations

  • Board member and director of education committee at the New Hampshire Academy of Science since 2016
  • Associate Member, American Association for Cancer Research since 2006

Education

  • Postdoctoral research, Dartmouth Medical School
  • Ph.D., University of New Hampshire
  • M.S., University of New Hampshire
  • B.S., Lake Erie College