Joined the faculty in 2008. Received Ph.D. in Pharmacology and Toxicology from Dartmouth Medical School in 1999. Areas of expertise include anatomy, physiology, microbiology, pharmacology, toxicology and cancer biology. read more…
Areas of Expertise
- Anatomy & Physiology
- Cancer Biology
Recent Presentations / Publications
De Biasio, A., Vrana, J.A., Zhou, P., Qian, L., Bieszczad, C.K., Braley, K.E., Domina, A.M., Weintraub, S.J., Neveu, J.M., Lane, W.S., Craig, R.W. N-Terminal Truncation of Antiapoptotic MCL1, But Not G2/M-Induced Phosphorylation, Is Associated With Stabilization and Abundant Expression in Tumor Cells, J. Biol. Chem. 282(33): 23919-36, 2007.
Vrana, J.A., Bieszczad, C.K., Cleaveland, E.S., Ma Y., Park, J.P., Mohandas, T.K., Craig, R.W. An MCL1-Overexpressing Burkitt Lymphoma Subline Exhibits Enhanced Survival on Exposure to Serum Deprivation, Topoisomerase Inhibitors, or Staurosporine But Remains Sensitive to 1-beta-D-arabinofuranosylcytosine, Cancer Research. Feb 1;62(3):892-900, 2002.
Townsend, K.J., Zhou, P, Bieszczad, C.K., Lowrey, C. and Craig, R.W. Regulation of MCL1 by Serum Response Factor / Elk-1-Mediated Mechanism Links Expression of a Viability-promoting Member of the BCL2 Family to Proliferation/Differentiation, J. Biol. Chem., 274(3):1801-13, 1999.
Zhou, P., Qian, L., Bieszczad, C.K., Noll, W.W., Noelle, R., Binder, M., Levy, N.B. and Craig, R.W. Mcl-1 in Transgenic Mice Promotes Survival in a Spectrum of Hematopoietic Cell Types, Allowing for Immortalization in the Myeloid Lineage, Blood, 92(9):3226-39, 1998.
Zhan, Q., Bieszczad, C.K., Bae, I., Fornace, A. Jr. and Craig, R.W. Induction of Bcl-2 Family Member Mcl-1 as an Early Response to DNA Damage, Oncogene 14(9), 1031-1039, 1997.
- Ph.D., Pharmacology and Toxicology, Dartmouth Medical School
- B.S., Biology with minors in Chemistry and Special Education, Saint Joseph College
- State of Connecticut Board Certified Teacher, Secondary Education, Biology